(ATI) Autologous Tenocyte Implantation

What is ATI?

Tendons can be very slow to heal if injured, and rarely regain their original strength. Partial tears heal by the rapid production of disorganized collagen, which is weaker than normal tendon. Recurrence of injury in the damaged region of tendon is common.

Autologous Tenocyte Implantation (ATI) is a new tissue engineering technique designed to assist and improve the regeneration of your damaged/injured tendon.

Procedure details

ATI involves firstly a biopsy procedure whereby a small piece of tendon is harvested from a healthy tendon (typically the tendon below the kneecap). Your biopsied tissue is taken to Orthocell’s specially designed and Government regulated laboratory where the building blocks of the tendon, the tenocyte cells, are isolated and grown over a period of approximately 4- 5 weeks. The cells are then implanted via injection into the affected tissue via ultrasound guidance.

Post procedure

We would expect the patient to rest the affected region for 48hrs. The patient can then return to routine daily activities and undertake light work duties, gradually progressing to increased activities in the subsequent weeks. It is important not to excessively repeat the movements that caused the injury initially.

Patients can normally recommence driving approximately 1 to 2 days following the treatment.

The patients improve steadily over a 6 month period as we are regenerating the cause not just treating the symptoms. We see improvement steadily from the 3 week period and by 6 months we can begin to draw conclusions as to the effectiveness of the outcome.

ATI success

There is documented scientific evidence supporting ATI cell therapy detailing its success in treating common tendinopathy. This procedure offers the potential for a re-generative approach to the degenerate and difficult to repair tendon. There is significant preclinical work and a growing body of evidence to support the use of ATI.

Information sourced and reproduced with permission from ortho.cell